SMLE

SMLEPhysiology MCQs

Practice 12 Physiology past-paper MCQs for SMLE, each with a detailed explanation and reference. Try free samples below, then start a full quiz.

Part of the full SMLE QBank — 2,948 questions across all subjects.

Physiology is a core part of the SMLE syllabus. HighYield's Physiology question bank collects 12MCQs modelled on real past papers, so you practise the exact style and difficulty you'll face on exam day. Every question comes with a worked explanation and a subject reference, so you learn why an answer is right — not just which option to pick.

Work through Physiology in Tutor mode to learn as you go, or switch to Timed mode to simulate real exam pressure. Your accuracy is tracked per subject, so you always know whether Physiology is a strength to maintain or a weak area to drill.

Sample Physiology Questions

Q1

Why is inulin used as the gold-standard marker for measuring glomerular filtration rate?

  • A.It is freely filtered by the glomerulus and neither secreted nor reabsorbed by the renal tubules
  • B.It binds plasma proteins, allowing accurate plasma level measurement
  • C.It is actively secreted by the proximal tubule
  • D.It is partially reabsorbed, providing an easily calculable correction factor
Q2

A person who recently moved to a high-altitude location develops an elevated hemoglobin with no other medical history. What is the cause?

  • A.Obstructive sleep apnea
  • B.Carbon monoxide poisoning
  • C.Increased erythropoietin production (physiologic response to hypoxia)
  • D.Polycythemia vera
Q3

A rare inherited cause of severe hyperuricemia and gout results from elevated activity of which enzyme, which drives increased purine synthesis?

  • A.Xanthine oxidase
  • B.Uricase
  • C.PRPP (phosphoribosyl pyrophosphate) synthetase
  • D.Adenosine deaminase

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