SMLE — Genetics MCQs
Practice 27 Genetics past-paper MCQs for SMLE, each with a detailed explanation and reference. Try free samples below, then start a full quiz.
Genetics is a core part of the SMLE syllabus. HighYield's Genetics question bank collects 27MCQs modelled on real past papers, so you practise the exact style and difficulty you'll face on exam day. Every question comes with a worked explanation and a subject reference, so you learn why an answer is right — not just which option to pick.
Work through Genetics in Tutor mode to learn as you go, or switch to Timed mode to simulate real exam pressure. Your accuracy is tracked per subject, so you always know whether Genetics is a strength to maintain or a weak area to drill.
Sample Genetics Questions
What is the mode of inheritance of cystic fibrosis?
- A.Autosomal dominant
- B.Mitochondrial
- C.Autosomal recessive
- D.X-linked recessive
A patient has features of Ehlers-Danlos syndrome (joint hypermobility, skin hyperextensibility and fragility). What is the mode of inheritance?
- A.Always autosomal recessive only
- B.Always mitochondrial
- C.Always X-linked recessive
- D.Most commonly autosomal dominant, though some subtypes are autosomal recessive
Which HLA gene is strongly associated with celiac disease, found in 80-90% of affected patients?
- A.HLA-DR3 only, without DQ association
- B.HLA-DQ2 (also associated with HLA-DQ8)
- C.HLA-B27
- D.HLA-DR4
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