SMLE — Genetics MCQs
Practice 27 Genetics past-paper MCQs for SMLE, each with a detailed explanation and reference. Try free samples below, then start a full quiz.
Part of the full SMLE QBank — 2,948 questions across all subjects.
Genetics is a core part of the SMLE syllabus. HighYield's Genetics question bank collects 27MCQs modelled on real past papers, so you practise the exact style and difficulty you'll face on exam day. Every question comes with a worked explanation and a subject reference, so you learn why an answer is right — not just which option to pick.
Work through Genetics in Tutor mode to learn as you go, or switch to Timed mode to simulate real exam pressure. Your accuracy is tracked per subject, so you always know whether Genetics is a strength to maintain or a weak area to drill.
Sample Genetics Questions
Which hemoglobinopathy is most common in the Mediterranean region?
- A.Sickle cell anemia (most common in sub-Saharan Africa and India)
- B.G6PD deficiency
- C.Alpha thalassemia (more common in Southeast Asia and Africa)
- D.Beta thalassemia
Which HLA gene is strongly associated with celiac disease, found in 80-90% of affected patients?
- A.HLA-DR3 only, without DQ association
- B.HLA-DQ2 (also associated with HLA-DQ8)
- C.HLA-B27
- D.HLA-DR4
What is the definitive prenatal/postnatal test to confirm a diagnosis of Down syndrome?
- A.Maternal serum screening alone, without confirmatory testing
- B.Non-invasive prenatal testing (cell-free DNA) alone, without confirmatory testing
- C.Chromosomal analysis via chorionic villus sampling or amniocentesis (prenatal) or karyotype (postnatal)
- D.Nuchal translucency ultrasound alone, without confirmatory testing
Sign in to see the correct answers and detailed explanations for every question.
Ready to master Genetics?
Start with 20 free questions — no card required.
Start free trial