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MDCAT · Biology

Transport, Circulation and Gaseous Exchange MCQs for MDCAT

52 practice MCQs on the human heart, blood vessels and blood, the respiratory system and gas exchange, lymph, and water and food transport in plants. Every question has the correct answer and an explanation.

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Transport, Circulation and Gaseous Exchange is part of the MDCAT Biology syllabus. This page collects Transport, Circulation and Gaseous Exchange MCQs in the style of past MDCAT papers — below are 12 of them with answers and explanations, and the full set of 52 questions is in the HighYield MDCAT QBank.

This chapter covers: the human heart, blood vessels and blood, the respiratory system and gas exchange, lymph, and water and food transport in plants.

Transport, Circulation and Gaseous Exchange MCQs with answers

Q1.Which of the following is a blood borne disease?

  • A.Hepatitis
  • B.Cholera
  • C.Influenza
  • D.Candidiasis
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Correct answer: A. Hepatitis

Hepatitis (B and C) is transmitted via blood and blood products, unlike cholera, influenza and candidiasis which spread by other routes.

Q2.The lymph vessel of villi is called:

  • A.Epithelium
  • B.Afferent lymph vessel
  • C.Adrenals
  • D.Lacteal
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Correct answer: D. Lacteal

The lymph vessel located within each intestinal villus, responsible for absorbing dietary fats, is called the lacteal.

Q3.Mature mammalian red blood cells do not have

  • A.Nucleus
  • B.Red color
  • C.Fluids
  • D.Haemoglobin
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Correct answer: A. Nucleus

Mature mammalian red blood cells lack a nucleus, having expelled it during development to maximize space for haemoglobin.

Q4.Which one of the following is the most numerous / commonest of white blood cells?

  • A.Eosinophils
  • B.Monocytes
  • C.Neutrophils
  • D.Lymphocytes
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Correct answer: D. Lymphocytes

Neutrophils are the most abundant type of white blood cell, forming the first line of defence against bacterial infection.

Q5.About 70-85% CO2 in blood is carried:

  • A.As carboxylase myoglobin
  • B.With proteins in plasma
  • C.Freely as CO2
  • D.As bicarbonate
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Correct answer: D. As bicarbonate

About 70-85% of CO2 in the blood is transported as bicarbonate ions, formed after CO2 combines with water in red blood cells.

Q6.Breathing consists of:

  • A.Four phases
  • B.Three phases
  • C.One phase
  • D.Two phases
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Correct answer: D. Two phases

Breathing consists of two phases: inspiration (inhalation) and expiration (exhalation).

Q7.T-lymphocytes recognize antigen and attack microorganisms or transplanted organ and tissues. This effect is called

  • A.Cell-mediated response
  • B.Humeral immune response
  • C.Active immunity
  • D.Passive immunity
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Correct answer: A. Cell-mediated response

When T-lymphocytes recognize and attack microorganisms or transplanted tissue directly, this is termed the cell-mediated immune response.

Q8.B-cells release antibodies in blood plasma, tissue fluid and lymph. This kind of immune response is called:

  • A.Cell Mediated Response
  • B.Humoral Response
  • C.Active Response
  • D.Compound Response
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Correct answer: B. Humoral Response

When B-cells (via plasma cells) release antibodies into blood plasma, tissue fluid and lymph, this is called the humoral immune response, as opposed to the cell-mediated response driven by T-cells.

Q9.How many possible alleles of ABO blood group are present in an individual?

  • A.1
  • B.2
  • C.3
  • D.300
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Correct answer: C. 3

The ABO blood group antigens are encoded by one genetic locus, the ABO locus, which has three alternative (allelic) forms—A, B, and O. A child receives one of the three alleles from each parent, giving rise to six possible genotypes and four possible blood types (phenotypes).

Q10.The ABO blood group is controlled by more than two alleles in a population. This shows that ABO blood group is an example of:

  • A.Polygenic Inheritance
  • B.Multiple Alleles
  • C.Operons
  • D.Allelic interaction
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Correct answer: B. Multiple Alleles

In the ABO blood group system, there are more than two alleles (A, B, and O) that control the blood type in a population. Each individual inherits two alleles from their parents, resulting in a combination of these multiple alleles determining their blood type.

Q11.Which of the following statements Is not correct about alveoli:

  • A.Alveoli form the gas exchange surface
  • B.The wall of each alveolus is 0.1 cm thick
  • C.Alveoli has a dense network of capillaries
  • D.Collagen and elastin present in alveoli allow it to expand and recoil easily during breathing
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Correct answer: B. The wall of each alveolus is 0.1 cm thick

Option B regarding alveoli is not correct.The walls of alveoli are extremely thin, only about 0.0002 cm thick. This allows for the rapid diffusion of gases between the alveoli and the blood capillaries that surround them.while all other statements regarding alveoli are correct.

Q12.In sickle cell, haemoglobin molecule, glutamic acid, is replaced by:

  • A.Proline
  • B.Glutamine
  • C.Valine
  • D.Glycine
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Correct answer: C. Valine

Option C is correct. In sickle cell anemia, glutamic acid in the hemoglobin molecule is replaced by valine. This single amino acid substitution leads to the hemoglobin molecules becoming sticky and clumping together when oxygen levels are low. This causes the formation of sickle-shaped red blood cells, which can obstruct blood vessels and lead to severe complications such as pain, stroke, and other health issues. Sickle cell anemia is a genetic condition resulting from a mutation in the hemoglobin gene and is especially prevalent among individuals of African descent. The other options (Proline, Glutamine, Glycine) do not correctly identify the amino acid involved in this specific mutation, and therefore, do not explain the pathology of sickle cell anemia.

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