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MDCAT · Biology

Acellular Life MCQs for MDCAT

32 practice MCQs on viruses, bacteriophages, viroids and prions, their structure, replication cycles and the diseases they cause. Every question has the correct answer and an explanation.

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Acellular Life is part of the MDCAT Biology syllabus. This page collects Acellular Life MCQs in the style of past MDCAT papers — below are 12 of them with answers and explanations, and the full set of 32 questions is in the HighYield MDCAT QBank.

This chapter covers: viruses, bacteriophages, viroids and prions, their structure, replication cycles and the diseases they cause.

Acellular Life MCQs with answers

Q1.The major cause of hepatitis B is

  • A.Blood transfusion
  • B.Blood clotting
  • C.Absence of fibrinogen
  • D.Contaminated soil
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Correct answer: A. Blood transfusion

Hepatitis B is chiefly transmitted through blood transfusion and other exposure to infected blood, not through clotting defects or soil.

Q2.Which one of the following diseases caused by enveloped RNA virus and spread in epidemic form?

  • A.Influenza
  • B.Herpes Simplex
  • C.Polio
  • D.Small Pox
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Correct answer: A. Influenza

Influenza is caused by an enveloped RNA virus and characteristically spreads in seasonal epidemic (and occasional pandemic) waves.

Q3.What are the sequence of steps in which a bacteriophage attacks bacteria and injects its DNA?

  • A.Landing > Tall contraction > Penetration > DNA Injection
  • B.Penetration > Landing > Tall contraction > DNA Injection
  • C.Tall contraction > Landing > DNA Injection > Penetration
  • D.Landing > Penetration > Tall contraction > DNA Injection
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Correct answer: A. Landing > Tall contraction > Penetration > DNA Injection

A bacteriophage infects a bacterium in sequence: landing on the cell surface, penetration of the tail, tail sheath contraction, then DNA injection.

Q4.All viruses can reproduce within living organisms only, so they are known as:

  • A.Ectoparasites
  • B.Endoparasites
  • C.Obligative Intracellular Parasites
  • D.Facultative Intracellular Parasites
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Correct answer: C. Obligative Intracellular Parasites

Viruses can only reproduce within a living host cell, making them obligate intracellular parasites.

Q5.What does the term bacteriophage refer to?

  • A.A virus that infects bacteria
  • B.A bacterium that infects virus
  • C.A virus which behaves as bacteria
  • D.Combination of Bacterium & Virion
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Correct answer: A. A virus that infects bacteria

A bacteriophage is a type of virus that specifically infects bacteria. It attaches to the surface of bacterial cells and injects its genetic material into the host, taking over the bacterial machinery to replicate itself.

Q6.How many tail fibrils are attached to the end plate of a bacteriophage?

  • A.2
  • B.4
  • C.6
  • D.8
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Correct answer: C. 6

Bacteriophages typically have tail fibers attached to the end plate. These tail fibers help the phage attach to specific receptors on the surface of the bacterial host cell. There are six long tail fibers attached to the end plate of a bacteriophage.

Q7.The molecules used to control viruses during infection of animal cells are:

  • A.Interferons
  • B.Histone
  • C.Antigen
  • D.Serum
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Correct answer: A. Interferons

Interferons are proteins that play a key role in controlling viral infections. They boost the body’s immune defenses and help limit the spread of viruses within the body. The other options listed (antigen, histone, and serum) are not molecules specifically used to control viruses during infection but may have other roles in immune responses or cellular processes.

Q8.The complete, mature & infectious particle of virus is known as:

  • A.Genome
  • B.Capsomere
  • C.Virion
  • D.Envelope
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Correct answer: C. Virion

A virion is the fully assembled, infectious form of a virus when it’s outside a host cell. It includes the genetic material along with its protective protein coat, and sometimes an envelope, allowing it to survive in the environment and infect new cells.

Q9.HIV belongs to a special class of virus known as:

  • A.Retrovirus
  • B.Flavivirus
  • C.Novavirus
  • D.Tetanus
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Correct answer: A. Retrovirus

HIV belongs to a special class of virus known as retrovirus. Retroviruses are a type of virus that uses RNA as its genetic material. They are also unique in that they use an enzyme called reverse transcriptase to convert their RNA genome into DNA. This DNA is then integrated into the host cell's genome, where it can be transcribed and translated into viral proteins. Retroviruses are responsible for a number of diseases in humans and animals, including HIV/AIDS, leukemia, and lymphoma. HIV is a retrovirus that attacks the immune system, making it difficult for the body to fight off infection.

Q10.The genome of the Human Immunodeficiency Virus (HIV) is made up of:

  • A.cDNA
  • B.DNA
  • C.RNA
  • D.rRNA
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Correct answer: C. RNA

HIV is a retrovirus with a genome made of two single-stranded RNA molecules, about 9,700 nucleotides long. It carries genes that code for its essential proteins. After entering a host cell, its RNA is converted into DNA by reverse transcriptase and then integrated into the host genome so the virus can replicate.

Q11.The protein coat surrounding the genome of virus is called:

  • A.Capsid
  • B.DNA sheath
  • C.Phage
  • D.Viroid
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Correct answer: A. Capsid

The capsule is an additional covering that surrounds the cell wall of some bacteria, providing protection against phagocytosis (engulfment by host cells), desiccation (drying out), Antibiotics and other antimicrobial agentsThe capsule is composed of polysaccharides (complex sugars) and can be found in both Gram-positive and Gram-negative bacteria.

Q12.Which of the following is an example of a sub-viral particle that infects plants?

  • A.Prion
  • B.Viroid
  • C.Bacteriophage
  • D.Infectious protein
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Correct answer: B. Viroid

Viroids are small, circular RNA molecules that can infect plants. They lack a protein coat and do not encode proteins, relying on the host's cellular machinery for replication. Viroids are responsible for various plant diseases, disrupting normal growth and development

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