MCCQE Part 1

MCCQE Part 1Pathology MCQs

Practice 17 Pathology past-paper MCQs for MCCQE Part 1, each with a detailed explanation and reference. Try free samples below, then start a full quiz.

Pathology is a core part of the MCCQE Part 1 syllabus. HighYield's Pathology question bank collects 17MCQs modelled on real past papers, so you practise the exact style and difficulty you'll face on exam day. Every question comes with a worked explanation and a subject reference, so you learn why an answer is right — not just which option to pick.

Work through Pathology in Tutor mode to learn as you go, or switch to Timed mode to simulate real exam pressure. Your accuracy is tracked per subject, so you always know whether Pathology is a strength to maintain or a weak area to drill.

Sample Pathology Questions

Q1

A 57-year-old man wakes from sleep with excruciating pain in his right big toe after a couple of recent drinking binges. The toe is red, warm, swollen, and exquisitely tender, with dark, shiny, tense overlying skin. Synovial fluid shows negatively birefringent needle-shaped crystals within neutrophils, and serum uric acid is markedly elevated. What is the most appropriate pharmacotherapy for this acute attack?

  • A.Indomethacin
  • B.Probenecid
  • C.Allopurinol
  • D.Ceftriaxone
Q2

A 50-year-old woman with varicose veins presents with marked ankle edema, erythema, mild scaling, and brownish discoloration of the skin over the distal lower legs. What is the most likely diagnosis?

  • A.Lichen simplex chronicus
  • B.Stasis dermatitis
  • C.Atopic dermatitis
  • D.Cellulitis
Q3

A 54-year-old man's brother developed sigmoid colon cancer at age 60; the patient has no other symptoms and a normal exam. What is the most appropriate colorectal cancer screening test for him?

  • A.Flexible sigmoidoscopy plus barium enema
  • B.Flexible sigmoidoscopy alone
  • C.Annual digital rectal exam and fecal occult blood testing
  • D.Colonoscopy

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