MCCQE Part 1

MCCQE Part 1Infectious Disease MCQs

Practice 43 Infectious Disease past-paper MCQs for MCCQE Part 1, each with a detailed explanation and reference. Try free samples below, then start a full quiz.

Infectious Disease is a core part of the MCCQE Part 1 syllabus. HighYield's Infectious Disease question bank collects 43MCQs modelled on real past papers, so you practise the exact style and difficulty you'll face on exam day. Every question comes with a worked explanation and a subject reference, so you learn why an answer is right — not just which option to pick.

Work through Infectious Disease in Tutor mode to learn as you go, or switch to Timed mode to simulate real exam pressure. Your accuracy is tracked per subject, so you always know whether Infectious Disease is a strength to maintain or a weak area to drill.

Sample Infectious Disease Questions

Q1

A 22-year-old man on cotrimoxazole (started 3 days ago for otitis media) presents with a 1-day history of lip erosions, conjunctivitis, and a blistering rash. His temperature is 37.9°C and he has no other systemic complaints. What is the best initial step in management?

  • A.Admit to hospital, monitor fluid status, and stop the antibiotic
  • B.Switch to a cephalosporin and send home
  • C.Refer to Dermatology for further outpatient investigation
  • D.Prescribe a course of topical steroids
Q2

A 40-year-old diabetic man presents with acute redness and swelling of the hand and forearm, with red streaks tracking up toward the axilla, local pain, and crepitus on palpation. Temperature is 40°C, pulse 110, and blood pressure 95/65 mmHg, with an elevated white cell count. Which organism is most likely responsible?

  • A.Group B Streptococcus
  • B.Group A Streptococcus
  • C.Viridans streptococcus
  • D.Staphylococcus epidermidis
Q3

For the diabetic patient above with crepitus and systemic toxicity from a rapidly spreading streptococcal soft-tissue infection, what is the most appropriate approach to therapy?

  • A.Observation with serial exams and oral antibiotics if it worsens
  • B.IV antibiotics alone
  • C.Oral antibiotics alone
  • D.Surgical debridement combined with IV antibiotics

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