UHS PGET Surgery & Allied (Group 1) MCQs by Subject: General Surgery, Anatomy & Pathology

Sample UHS PGET Surgery & Allied (Group 1) MCQs from General Surgery, Anatomy and Pathology — the three biggest subjects in HighYield's Group 1 bank.

UHS PGET Surgery & Allied (Group 1) pulls its heaviest volume from General Surgery, Anatomy and Pathology — together the three biggest subjects in HighYield's Group 1 bank. Below is a sample from each, with the reasoning behind every answer.

General Surgery

1. Murphy's sign — pain and a pause in inspiration on palpation of the right upper quadrant — points to which diagnosis?

A) Acute appendicitis
B) Acute pancreatitis
C) Acute cholecystitis ✅
D) Perforated duodenal ulcer

An inflamed gallbladder touching the examiner's fingers during inspiration causes a reflex pause in breathing — the basis of Murphy's sign in acute cholecystitis.

2. A perforated peptic ulcer is most commonly found at which site?

A) Lesser curvature of the stomach
B) Anterior wall of the first part of the duodenum ✅
C) Pylorus
D) Posterior wall of the first part of the duodenum

Anterior duodenal ulcers perforate into the peritoneal cavity, causing free air and peritonitis; posterior ulcers instead erode into the gastroduodenal artery and bleed rather than perforate.

Anatomy

3. The posterior wall of the inguinal canal is formed mainly by which structure?

A) External oblique aponeurosis
B) Conjoint tendon and transversalis fascia ✅
C) Inguinal ligament
D) Internal oblique muscle

Transversalis fascia forms the posterior wall throughout, reinforced medially by the conjoint tendon — the weak point exploited in direct inguinal hernias.

4. Injury to which nerve during thyroid surgery changes voice pitch without causing hoarseness or airway compromise?

A) Recurrent laryngeal nerve
B) External laryngeal nerve ✅
C) Internal laryngeal nerve
D) Hypoglossal nerve

The external laryngeal nerve supplies cricothyroid, which tenses the vocal cords; injury flattens the voice's upper range but, unlike recurrent laryngeal nerve injury, does not cause hoarseness or stridor.

Pathology

5. Signet ring cells on biopsy are characteristic of which malignancy?

A) Diffuse-type gastric carcinoma ✅
B) Intestinal-type gastric carcinoma
C) Gastric lymphoma
D) Gastrointestinal stromal tumour

Mucin-filled cells pushing the nucleus to the periphery give the signature "signet ring" appearance, typical of diffuse-type (poorly cohesive) gastric adenocarcinoma, which spreads by direct infiltration rather than forming a discrete mass.

6. The most common benign breast tumour in women under 30 is:

A) Phyllodes tumour
B) Intraductal papilloma
C) Fibroadenoma ✅
D) Fat necrosis

Fibroadenomas are hormone-sensitive, well-circumscribed, mobile ("breast mouse") lumps that are by far the most common benign breast tumour in young women.

Why This Mix Still Decides Your Score

Group 1 candidates often over-index their revision on operative surgery topics and under-revise the basic sciences that still make up a large share of the paper. In HighYield's Group 1 bank, General Surgery, Anatomy and Pathology are the three largest subjects by question volume — skipping any of them is a measurable risk.

HighYield's UHS PGET Surgery & Allied (Group 1) question bank covers every subject in both papers, each question explained. For a broader sample, see our UHS PGET Surgery Group 1 MCQs guide, or read the PGET exam pattern guide first.