Most Repeated FCPS Part 1 Medicine MCQs: High-Yield Subjects

The subjects that carry the most weight in FCPS Part 1 Medicine — Anatomy, Pathology and Pharmacology — with sample MCQs for each.

FCPS Part 1 Medicine is a basic-sciences paper first — the largest subjects by question count are Anatomy, Pathology and Pharmacology, ahead of clinical Medicine itself. Below is a sample across the highest-weight subjects.

Anatomy

1. The vagus nerve is which cranial nerve?

A) IX
B) X ✅
C) XI
D) XII

Physiology

2. The normal resting adult heart rate range is:

A) 40–60 bpm
B) 60–100 bpm ✅
C) 100–120 bpm
D) 120–140 bpm

Pathology

3. The type of necrosis classically seen in tuberculous granulomas is:

A) Coagulative necrosis
B) Liquefactive necrosis
C) Caseous necrosis ✅
D) Fat necrosis

Pharmacology

4. ACE inhibitors lower blood pressure primarily by blocking the conversion of:

A) Renin to angiotensin I
B) Angiotensin I to angiotensin II ✅
C) Angiotensin II to aldosterone
D) Aldosterone to cortisol

Biochemistry

5. Which cardiac biomarker is most specific for myocardial infarction?

A) CK-MB
B) Troponin ✅
C) Myoglobin
D) LDH

Microbiology

6. Staphylococcus aureus is classified as:

A) Gram-negative cocci
B) Gram-positive cocci ✅
C) Gram-negative bacilli
D) Gram-positive bacilli

Why the Basic Sciences Carry This Much Weight

Because FCPS Part 1 tests foundational knowledge rather than clinical management, a candidate who's strong in Anatomy, Physiology, Pathology and Pharmacology will out-perform one who's only revised clinical Medicine topics — the paper is built to test the science underneath the clinic, not the clinic itself.

Looking for a Mock Exam, Not Just More Questions to Read?

If what you actually want is a timed FCPS Part 1 Medicine mock exam — not another static list to read through — that's exactly what the free sample on the Medicine question bank page gives you: the same timed, explained format as the full bank, no separate "mock test" product to buy or download.

HighYield's FCPS Part 1 Medicine bank covers all of these subjects, each question explained. Try the first 20 questions free, no sign-in required, from the FCPS Part 1 Medicine question bank page.