SZABMU MS Part-I Paper II MCQs: Endocrine, GIT, Neurosurgery & Urology

Endocrine, GIT and neurosurgery are 10% each of SZABMU MS Part-I Paper II, and urology adds 5%. The questions blend surgical anatomy, investigation and management. Here is a sample from our MS bank.

Sample MCQs

1. A patient with periodic hypertension and sweating is started on alpha blockade preoperatively. What is the likely diagnosis?

• A) Adrenal adenoma
• B) Medulloblastoma
• C) Phaeochromocytoma ✅
• D) Neuroblastoma

Alpha blockade before surgery prevents hypertensive crisis in phaeochromocytoma, which causes paroxysmal hypertension and sweating.

2. Which hormone decreases in the stress response?

• A) Cortisol
• B) Growth hormone
• C) Thyroxine ✅
• D) Adrenaline

Cortisol, GH and catecholamines rise in stress, while thyroxine and sex hormones fall.

3. A child with abdominal pain is suspected of having intussusception. Which of the following is true?

• A) Vomiting occurs early in presentation
• B) Currant-jelly red stools are pathognomonic ✅
• C) Fever excludes intussusception as a diagnosis
• D) The condition occurs in under 3-month-olds in 70% of cases

Currant-jelly stool (blood and mucus) is the classic finding in intussusception, which typically occurs between 3 months and 3 years.

4. A 50-year-old known case of peptic ulcer disease presents with multiple episodes of haematemesis. He is unstable with BP 90/50 and pulse 115/min. After initial resuscitation, what step should be done?

• A) Insertion of ETT
• B) Early endoscopy ✅
• C) Insert Sengstaken-Blakemore tube
• D) Start terlipressin

After resuscitation, upper GI endoscopy within 24 hours is the diagnostic and therapeutic step in suspected non-variceal bleeding.

5. BP 170/100, pinpoint pupils, patient can blink and move eyes up and down but is otherwise paralysed. What could be the cause?

• A) OP poisoning
• B) Midbrain stroke
• C) Hypoglycaemia
• D) Pontine stroke ✅

Quadriplegia with preserved vertical eye movements and blinking and pinpoint pupils is the locked-in syndrome from a basilar (pontine) infarct or haemorrhage.

6. Why does levodopa therapy wane in effect with time?

• A) Dopamine levels in the brain decrease as the disease progresses ✅
• B) Tachyphylaxis develops
• C) The efficacy of carbidopa decreases with time
• D) Enzymes that break down levodopa increase with time

Progressive loss of nigrostriatal neurons reduces dopamine storage capacity, causing wearing-off and fluctuations.

7. In nosocomial UTIs, the flora is found from where in two-thirds of the cases?

• A) Hands of medical personnel
• B) Patient's own flora ✅
• C) Flora colonising hospital bathrooms
• D) Hospital beds

Most nosocomial UTIs arise from the patient's own bowel and perineal flora introduced by catheterisation.

8. The commonest site for prostate cancer is:

• A) Median lobe
• B) Posterior lobe ✅
• C) Anterior lobe
• D) Lateral lobe

Most prostate carcinomas arise in the peripheral zone (posterior lobe), which is palpable on digital rectal examination.

Study Notes

• Endocrine surgery: thyroid, parathyroid and adrenal conditions with the usual investigation and surgical complication.
• GIT: dysphagia, obstruction, bleeding and hernia basics.
• Neurosurgery: head injury grading, haematoma types and spinal cord syndromes.
• Urology: stones, BPH and testicular conditions.

Practise in the Endocrine, GIT and Neurosurgery sections of the SZABMU MS QBank. The fluids, sepsis and infection block is in this post, and Paper I is in anatomy and physiology MCQs.

Frequently Asked Questions

How much is neurosurgery worth?

10% of Paper II, about 10 MCQs.

Where is urology weighted?

5% of Paper II.

Practise With Explanations

The SZABMU MS QBank groups its MCQs by the official Paper I and Paper II surgical topics, with an explanation for every question and topic analytics to show where marks are leaking. The first 20 questions are free, and the mock tests come included with the QBank. The MD bank shares the same Paper I core and swaps Paper II for applied medicine.