SZABMU MD Part-I Paper II MCQs: Haematology, Endocrine, Neurology & Nephrology

Haematology, endocrinology and diabetes, and hepatology and nephrology are 10% each of SZABMU MD Part-I Paper II, with neurology and rheumatology at 8%: 38 marks in all. Here is a sample set from our MD bank.

Sample MCQs

1. Pernicious anaemia is associated with deficiency of:

• A) Vitamin B1
• B) Vitamin B12 ✅
• C) Folic acid
• D) Vitamin B6

Pernicious anaemia is autoimmune loss of intrinsic factor, causing vitamin B12 deficiency.

2. A child with pica, 6-8 feeds of milk per day and minimal solid intake: which investigation will you do?

• A) Serum ferritin ✅
• B) Differential retics count
• C) LDH
• D) Bilirubin levels

Pica with a milk-dominated diet suggests iron deficiency anaemia, assessed by serum ferritin.

3. Acanthosis nigricans occurs in which of the following diseases?

• A) Cushing's
• B) Diabetes ✅
• C) Addison's
• D) SLE

Acanthosis nigricans is a marker of insulin resistance and is associated with type 2 diabetes and obesity.

4. A patient with hyperparathyroidism has bone pain. You are asked about brown tumours of the bone. What is this called?

• A) Osteitis fibrosa cystica ✅
• B) Osteitis deformans
• C) Osteochondritis dissecans
• D) Paget disease of the bone

Osteitis fibrosa cystica is the bone disease of hyperparathyroidism, with osteoclastic resorption forming brown tumours.

5. A 30-year-old woman has numbness and paraesthesias of both hands, especially in the early morning. Which nerve is involved?

• A) Median nerve ✅
• B) Axillary nerve
• C) Radial nerve
• D) Ulnar nerve

Bilateral night and morning hand numbness with tingling in the thumb, index and middle fingers is median nerve compression in carpal tunnel syndrome.

6. An old man with altered state of consciousness and left-sided body weakness has CT-proven ischaemia of the left temporal region. Which associated symptom is expected?

• A) Pinpoint pupils
• B) Ptosis of the left eye
• C) Aphasia ✅
• D) Left homonymous hemianopia

Dominant temporal lobe ischaemia involves Wernicke's area and causes aphasia.

7. A patient presents with a raised alpha-fetoprotein, splenomegaly with raised splenic index, heterogeneous liver parenchyma with a shrunken liver. What is the likely diagnosis?

• A) Hepatitis C
• B) Hepatocellular carcinoma ✅
• C) Fatty liver
• D) Hepatitis B

A raised AFP in a cirrhotic liver is hepatocellular carcinoma until proven otherwise.

8. A young girl with jaundice, nausea and vomiting and abdominal pain with fever. AST and ALT are deranged. What could be the cause?

• A) Hepatitis A ✅
• B) Leishmaniasis
• C) Falciparum malaria
• D) Haemolytic anaemia

Acute fever, jaundice and markedly raised transaminases in a young patient indicate acute viral hepatitis such as hepatitis A.

Study Notes

• Haematology: anaemia patterns, coagulation tests and the classic leukaemia and lymphoma associations.
• Endocrinology: thyroid, adrenal and diabetes emergencies.
• Neurology and rheumatology: localisation and the autoimmune disease associations.
• Hepatology and nephrology: liver function patterns, nephrotic versus nephritic syndromes and electrolyte effects.

Practise by topic in the Haematology, Endocrinology and Neurology sections of the SZABMU MD QBank. The first half of Paper II is covered in cardiovascular, respiratory and gastroenterology MCQs.

Frequently Asked Questions

What is the weightage of neurology and rheumatology?

8% of Paper II, about 8 MCQs.

Which Paper II topics are only 5%?

Immunology and ICU care.

Practise With Explanations

The SZABMU MD QBank groups its MCQs by the official Paper I and Paper II topics, with an explanation for every question and topic analytics to show where marks are leaking. The first 20 questions are free, and the mock tests come included with the QBank. The MS bank shares the same Paper I core and swaps Paper II for applied surgery.