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MDCAT Biology MCQs by Chapter: Cell Biology, Genetics & Reproduction

Chapter-wise MDCAT Biology practice — Cell Biology, Genetics, Reproduction and Support & Movement, the four highest-weight topic areas, with sample MCQs for each.

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Biology carries the most marks of any MDCAT subject, and within it, four chapters consistently carry disproportionate weight: Cell Biology, Genetics, Reproduction, and Support & Movement. Rather than one flat MDCAT Biology post, here's a chapter-by-chapter sample so you can see exactly where each concept sits.

Chapter: Cell Biology

1. Which organelle is responsible for protein synthesis?

  • A) Golgi apparatus
  • B) Ribosome ✅
  • C) Lysosome
  • D) Mitochondrion

2. The cell membrane is primarily composed of:

  • A) Cellulose
  • B) Phospholipid bilayer ✅
  • C) Chitin
  • D) Peptidoglycan

3. Which process allows water to move across a cell membrane from low to high solute concentration?

  • A) Active transport
  • B) Osmosis ✅
  • C) Facilitated diffusion
  • D) Exocytosis

Chapter: Genetics

4. In a monohybrid cross between two heterozygous parents (Aa × Aa), what phenotypic ratio is expected?

  • A) 1:1
  • B) 1:2:1
  • C) 3:1 ✅
  • D) 9:3:3:1

5. DNA replication is described as semi-conservative because:

  • A) Half the DNA is destroyed
  • B) Each new molecule has one original and one new strand ✅
  • C) Only half the genome replicates
  • D) Replication occurs only in half the cells

Chapter: Reproduction

6. Fertilization in humans normally occurs in the:

  • A) Uterus
  • B) Ovary
  • C) Fallopian tube ✅
  • D) Cervix

7. The hormone primarily responsible for triggering ovulation is:

  • A) Estrogen
  • B) Progesterone
  • C) Luteinizing hormone (LH) ✅
  • D) FSH

Chapter: Support & Movement

8. The protein primarily responsible for muscle contraction, working alongside myosin, is:

  • A) Collagen
  • B) Actin ✅
  • C) Keratin
  • D) Elastin

9. Which type of joint allows the widest range of movement, as found in the shoulder?

  • A) Hinge joint
  • B) Pivot joint
  • C) Ball-and-socket joint ✅
  • D) Gliding joint

Why Chapter-by-Chapter Beats a Flat Question List

MDCAT Biology's syllabus is broad enough that a single undifferentiated "MDCAT Biology MCQs" post either goes too shallow across everything or too deep into one area at random. Working chapter by chapter lets you find and drill your specific weak areas instead of re-reading material you've already mastered.

HighYield's MDCAT question bank is organized by subject and topic across all four MDCAT subjects, every question explained. For the concepts that repeat most often across all subjects, see our Most Repeated MDCAT MCQs by Subject. Try the first 20 questions of the full bank free, no sign-in required, from the MDCAT question bank page.

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