FCPS Part 1 Gynae/Obs MCQs by Subject: Biochemistry, Gynaecology, Microbiology & Forensic Medicine

Sample FCPS Part 1 Gynae/Obs MCQs from Biochemistry, Gynaecology, Microbiology and Forensic Medicine, each with a full explanation.

Alongside Anatomy, Pharmacology and Pathology, HighYield's Gynae/Obs question bank also draws on Biochemistry, Gynaecology, Microbiology and Forensic Medicine — four subjects that don't yet have dedicated practice coverage. Below is a sample across all four.

Biochemistry

1. Human chorionic gonadotropin (hCG) shares an identical alpha subunit with LH, FSH and TSH; pregnancy tests instead detect its:

A) Alpha subunit
B) Beta subunit ✅
C) Full intact molecule only, never a subunit
D) Signal peptide

2. Periconceptional folic acid supplementation is recommended primarily to reduce the risk of:

A) Gestational diabetes
B) Neural tube defects ✅
C) Pre-eclampsia
D) Placenta previa

Gynaecology

3. Per the Rotterdam criteria, a diagnosis of PCOS requires at least two of three features: oligo/anovulation, clinical or biochemical hyperandrogenism, and:

A) Elevated FSH
B) Polycystic ovarian morphology on ultrasound ✅
C) Elevated prolactin
D) Endometrial hyperplasia on biopsy

4. The most common type of ovarian cyst in a woman of reproductive age is a:

A) Dermoid cyst
B) Functional (follicular) cyst ✅
C) Endometrioma
D) Serous cystadenoma

Microbiology

5. A neonate with chorioretinitis, hydrocephalus and intracranial calcifications was most likely infected in utero with:

A) Cytomegalovirus
B) Toxoplasma gondii ✅
C) Rubella virus
D) Herpes simplex virus

6. Universal screening at 35–37 weeks' gestation is recommended to detect maternal colonisation with:

A) Escherichia coli
B) Group B Streptococcus (Streptococcus agalactiae) ✅
C) Candida albicans
D) Chlamydia trachomatis

Forensic Medicine

7. Regarding hymenal examination in medico-legal practice, which statement is correct?

A) An intact hymen conclusively proves virginity
B) A torn hymen conclusively proves prior intercourse
C) Hymenal appearance alone cannot reliably confirm or exclude sexual intercourse ✅
D) The hymen fully regenerates after each delivery

8. Before conducting a medico-legal examination of an alleged sexual assault survivor, the examining doctor's first priority is:

A) Collecting evidence before anything else
B) Obtaining informed consent ✅
C) Notifying the police directly
D) Completing the exam as quickly as possible

Why These Subjects Still Matter

Biochemistry, Gynaecology, Microbiology and Forensic Medicine are tested at FCPS Part 1 depth — integrated with obstetric and gynaecological scenarios rather than asked as isolated MBBS-level recall.

HighYield's FCPS Part 1 Gynaecology & Obstetrics question bank covers every subject in the paper, each question explained. For the full syllabus and duration, see our FCPS Gynae/Obs syllabus guide. Try the first 20 questions free, no sign-in required.