FCPS Part 1 Gynae/Obs MCQs by Subject: Anatomy, Pharmacology & Pathology

Sample FCPS Part 1 Gynae & Obs MCQs from the paper's largest basic-science subjects — Pharmacology, Anatomy and Pathology — each with the correct answer explained.

Like every FCPS Part 1 paper, Gynaecology & Obstetrics draws heavily on the basic sciences alongside clinical Gynae/Obs itself. In HighYield's Gynae/Obs question bank, Pharmacology, Anatomy and Pathology are three of the largest named subjects by question volume after the core Gynae/Obs pool. Below is a sample across all three, with a pelvic and obstetric focus.

Anatomy

1. The ovarian artery, supplying the ovary, arises directly from the:

A) Internal iliac artery
B) Uterine artery
C) Abdominal aorta ✅
D) External iliac artery

2. The rectouterine pouch (Pouch of Douglas) is the most dependent part of the peritoneal cavity in a woman lying:

A) Prone
B) Supine ✅
C) Lateral
D) Trendelenburg

3. The broad ligament of the uterus contains all of the following except:

A) Fallopian tube
B) Round ligament
C) Ovarian ligament
D) Sacrouterine (uterosacral) ligament ✅

Pharmacology

4. Oxytocin, used to induce or augment labour, acts primarily by:

A) Relaxing the myometrium
B) Stimulating rhythmic myometrial contractions ✅
C) Ripening the cervix via prostaglandin release only
D) Blocking calcium channels

5. Methotrexate, used for medical management of an unruptured ectopic pregnancy, works by:

A) Inhibiting folic acid metabolism, halting trophoblast division ✅
B) Blocking progesterone receptors
C) Inducing uterine contractions
D) Inhibiting prostaglandin synthesis

6. Magnesium sulfate is the drug of choice for seizure prophylaxis and treatment in:

A) Gestational diabetes
B) Eclampsia ✅
C) Placenta previa
D) Hyperemesis gravidarum

Pathology

7. A complete hydatidiform mole most commonly has which karyotype?

A) 69XXY
B) 46XX, entirely of paternal origin ✅
C) 46XY, entirely maternal origin
D) 45X

8. Painless, bright red vaginal bleeding in the third trimester is most characteristic of:

A) Placental abruption
B) Placenta previa ✅
C) Uterine rupture
D) Vasa previa alone

9. Endometriosis is defined as the presence of endometrial-type glands and stroma:

A) Within the myometrium only
B) Outside the uterine cavity ✅
C) In the cervix only
D) In the fallopian tube lumen only

Why the Basic Sciences Still Decide Your Score

Anatomy, Pharmacology and Pathology are tested at FCPS Part 1 depth — integrated with obstetric and gynaecological scenarios rather than asked as isolated MBBS-level recall. In HighYield's own Gynae/Obs bank, these three subjects together make up a substantial share of the question pool.

HighYield's FCPS Part 1 Gynaecology & Obstetrics question bank covers every subject in the paper, each question explained. For the full syllabus and duration, see our FCPS Gynae/Obs syllabus guide. Try the first 20 questions free, no sign-in required.